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HR+ HER2- Breast Cancer Resource Center

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Adjuvant dose-dense chemotherapy in hormone receptor-positive breast cancer

Last Updated: Friday, July 17, 2026

Researchers evaluated the 12-year outcomes of the C9741 trial to identify patients most likely to benefit from dose-dense chemotherapy. They found that low endocrine activity in the cancer was a predictor of benefit.

Journal of Clinical Oncology
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